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Design and analysis of confirmatory adaptive clinical trials with continuous, binary, and survival endpoints according to the methods described in the monograph by Wassmer and Brannath (2016) doi:10.1007/978-3-319-32562-0. This includes classical group sequential as well as multi-stage adaptive hypotheses tests that are based on the combination testing principle.
www.rpact.org | |
www.rpact.com | |
github.com/rpact-com/rpact | |
rpact-com.github.io/rpact/ | |
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