qtl2pleio

Testing Pleiotropy in Multiparental Populations

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We implement an adaptation of Jiang & Zeng's (1995) https://www.genetics.org/content/140/3/1111 likelihood ratio test for testing the null hypothesis of pleiotropy against the alternative hypothesis, two separate quantitative trait loci. The test differs from that in Jiang & Zeng (1995) https://www.genetics.org/content/140/3/1111 and that in Tian et al. (2016) doi:10.1534/genetics.115.183624 in that our test accommodates multiparental populations.


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