CRAN/E | posologyr

posologyr

Individual Dose Optimization using Population Pharmacokinetics

Installation

About

Determine individual pharmacokinetic (and pharmacokinetic-pharmacodynamic) profiles and use them to personalise drug regimens. You provide the data and a population pharmacokinetic model, 'posologyr' provides the individual a posteriori estimate and allows you to determine the optimal dosing. The empirical Bayes estimates are computed as described in Kang et al. (2012) doi:10.4196/kjpp.2012.16.2.97.

Citation posologyr citation info
levenc.github.io/posologyr/
github.com/levenc/posologyr
Bug report File report

Key Metrics

Version 1.2.4
R ≥ 3.5.0
Published 2024-02-09 88 days ago
Needs compilation? no
License AGPL-3
CRAN checks posologyr results

Downloads

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Last 7 days 69 -32%
Last 30 days 276 +2%
Last 90 days 860 +2%
Last 365 days 2.941

Maintainer

Maintainer

Cyril Leven

cyril.leven@chu-brest.fr

Authors

Cyril Leven

aut / cre / cph

Matthew nfidler

ctb

Emmanuelle Comets

ctb

Audrey Lavenu

ctb

Marc Lavielle

ctb

Material

README
NEWS
Reference manual
Package source

In Views

Pharmacokinetics

Vignettes

A posteriori dose selection
A priori dose selection
AUC-based dose selection
Multiple endpoints
Patient data input
User defined models

macOS

r-release

arm64

r-oldrel

arm64

r-release

x86_64

Windows

r-devel

x86_64

r-release

x86_64

r-oldrel

x86_64

Old Sources

posologyr archive

Depends

R ≥ 3.5.0

Imports

rxode2
stats
mvtnorm
data.table

Suggests

lotri
knitr
rmarkdown
testthat ≥ 3.0.0
ggplot2
magrittr
tidyr