Installation
About
Provides functions to implement and simulate the partial order continual reassessment method (PO-CRM) of Wages, Conaway and O'Quigley (2011) doi:10.1177/1740774511408748 for use in Phase I trials of combinations of agents. Provides a function for generating a set of initial guesses (skeleton) for the toxicity probabilities at each combination that correspond to the set of possible orderings of the toxicity probabilities specified by the user.
Key Metrics
Downloads
| Yesterday | 32 |
| Last 7 days | 47 +38% |
| Last 30 days | 221 -21% |
| Last 90 days | 938 +50% |
| Last 365 days | 3.036 -20% |