CRAN/E | nlmixr2

nlmixr2

Nonlinear Mixed Effects Models in Population PK/PD

Installation

About

Fit and compare nonlinear mixed-effects models in differential equations with flexible dosing information commonly seen in pharmacokinetics and pharmacodynamics (Almquist, Leander, and Jirstrand 2015 doi:10.1007/s10928-015-9409-1). Differential equation solving is by compiled C code provided in the 'rxode2' package (Wang, Hallow, and James 2015 doi:10.1002/psp4.12052).

Citation nlmixr2 citation info
nlmixr2.org/
github.com/nlmixr2/nlmixr2/
Bug report File report

Key Metrics

Version 2.1.1
Published 2024-02-01 84 days ago
Needs compilation? no
License GPL (≥ 3)
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Maintainer

Maintainer

Matthew Fidler

matthew.fidler@gmail.com

Authors

Matthew Fidler

aut / cre

Yuan Xiong

ctb

Rik Schoemaker

ctb

Justin Wilkins

ctb

Wenping Wang

ctb

Mirjam Trame

ctb

Huijuan Xu

ctb

John Harrold

ctb

Bill Denney

ctb

Theodoros Papathanasiou

ctb

Teun Post

ctb

Richard Hooijmaijers

ctb

Material

README
NEWS
Reference manual
Package source

In Views

DifferentialEquations
HighPerformanceComputing
MixedModels
Pharmacokinetics

macOS

r-release

arm64

r-oldrel

arm64

r-release

x86_64

Windows

r-devel

x86_64

r-release

x86_64

r-oldrel

x86_64

Old Sources

nlmixr2 archive

Depends

nlmixr2data

Imports

nlmixr2est ≥ 2.2.0
nlmixr2extra
rxode2 ≥ 2.1.1
lotri
nlmixr2plot
magrittr
crayon
cli

Suggests

rmarkdown
knitr
devtools
ggplot2
testthat
n1qn1
rxode2parse
withr

Reverse Depends

babelmixr2

Reverse Imports

nlmixr2rpt

Reverse Suggests

ggPMX
tidyvpc
xpose.nlmixr2