mr.pivw

Penalized Inverse-Variance Weighted Estimator for Mendelian Randomization

CRAN Package

The penalized inverse-variance weighted (pIVW) estimator is a Mendelian randomization method for estimating the causal effect of an exposure variable on an outcome of interest based on summary-level GWAS data. The pIVW estimator accounts for weak instruments and balanced horizontal pleiotropy simultaneously. See Xu S., Wang P., Fung W.K. and Liu Z. (2022) doi:10.1111/biom.13732.

  • Version0.1.1
  • R versionunknown
  • LicenseGPL-2
  • Needs compilation?No
  • Last release09/09/2022

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