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Ratios of count data such as obtained from RNA-seq are modelled using Bayesian statistics to derive posteriors for effects sizes. This approach is described in Erhard & Zimmer (2015) doi:10.1093/nar/gkv696 and Erhard (2018) doi:10.1093/bioinformatics/bty471.
github.com/erhard-lab/lfc | |
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