CRAN/E | gsDesign2

gsDesign2

Group Sequential Design with Non-Constant Effect

Installation

About

The goal of 'gsDesign2' is to enable fixed or group sequential design under non-proportional hazards. To enable highly flexible enrollment, time-to-event and time-to-dropout assumptions, 'gsDesign2' offers piecewise constant enrollment, failure rates, and dropout rates for a stratified population. This package includes three methods for designs: average hazard ratio, weighted logrank tests in Yung and Liu (2019) doi:10.1111/biom.13196, and MaxCombo tests. Substantial flexibility on top of what is in the 'gsDesign' package is intended for selecting boundaries.

merck.github.io/gsDesign2/
github.com/Merck/gsDesign2
Bug report File report

Key Metrics

Version 1.1.2
R ≥ 3.5.0
Published 2024-04-09 19 days ago
Needs compilation? yes
License GPL-3
CRAN checks gsDesign2 results

Downloads

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Maintainer

Maintainer

Yujie Zhao

yujie.zhao@merck.com

Authors

Keaven Anderson

aut

Yilong Zhang

aut

Yujie Zhao

aut / cre

Jianxiao Yang

aut

Nan Xiao

aut

Amin Shirazi

ctb

Ruixue Wang

ctb

Yi Cui

ctb

Ping Yang

ctb

Xin Tong Li

ctb

Chenxiang Li

ctb

Hiroaki Fukuda

ctb

Hongtao Zhang

ctb

Yalin Zhu

ctb

John Blischak

ctb

Dickson Wanjau

ctb

Merck & Co.
Inc.
Rahway
NJ
USA
its affiliates

cph

Material

README
NEWS
Reference manual
Package source

Vignettes

Quick start for NPH sample size and power

macOS

r-release

arm64

r-oldrel

arm64

r-release

x86_64

Windows

r-devel

x86_64

r-release

x86_64

r-oldrel

x86_64

Old Sources

gsDesign2 archive

Depends

R ≥ 3.5.0

Imports

corpcor
data.table
dplyr
gsDesign
gt
methods
mvtnorm
npsurvSS
r2rtf
stats
survival
tibble
tidyr
utils
Rcpp

Suggests

covr
ggplot2
kableExtra
knitr
rmarkdown
simtrial
testthat ≥ 3.0.0

LinkingTo

Rcpp

Reverse Suggests

simtrial