CRAN/E | grmsem

grmsem

Genetic-Relationship-Matrix Structural Equation Modelling (GRMSEM)

Installation

About

Quantitative genetics tool supporting the modelling of multivariate genetic variance structures in quantitative data. It allows fitting different models through multivariate genetic-relationship-matrix (GRM) structural equation modelling (SEM) in unrelated individuals, using a maximum likelihood approach. Specifically, it combines genome-wide genotyping information, as captured by GRMs, with twin-research-based SEM techniques, St Pourcain et al. (2017) doi:10.1016/j.biopsych.2017.09.020, Shapland et al. (2020) doi:10.1101/2020.08.14.251199.

CRAN.R-project.org/package=grmsem
gitlab.gwdg.de/beate.stpourcain/grmsem
Bug report File report

Key Metrics

Version 1.1.0
R ≥ 3.5
Published 2021-01-29 1186 days ago
Needs compilation? no
License GPL-3
CRAN checks grmsem results

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Maintainer

Maintainer

Beate StPourcain

Beate.StPourcain@mpi.nl

Authors

Beate StPourcain

aut / cre

Alexander Klassmann

ctb

Material

Reference manual
Package source

Vignettes

Vignette for package *grmsem*

macOS

r-release

arm64

r-oldrel

arm64

r-release

x86_64

r-oldrel

x86_64

Windows

r-devel

x86_64

r-release

x86_64

r-oldrel

x86_64

Depends

R ≥ 3.5

Imports

msm ≥ 1.6
numDeriv
optimParallel
stats
utils

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