Installation
About
A minimal set of routines to calculate the 'Grantham' distance doi:10.1126/science.185.4154.862. The 'Grantham' distance attempts to provide a proxy for the evolutionary distance between two amino acids based on three key chemical properties: composition, polarity and molecular volume. In turn, evolutionary distance is used as a proxy for the impact of missense mutations. The higher the distance, the more deleterious the substitution is expected to be.
| maialab.org/grantham/ | |
| github.com/maialab/grantham | |
| Bug report | File report |
Key Metrics
Downloads
| Yesterday | 12 0% |
| Last 7 days | 62 0% |
| Last 30 days | 186 +12% |
| Last 90 days | 486 -36% |
| Last 365 days | 2.327 -20% |