CRAN/E | frequentistSSD

frequentistSSD

Screened Selection Design with Survival Endpoints

Installation

About

A study based on the screened selection design (SSD) is an exploratory phase II randomized trial with two or more arms but without concurrent control. The primary aim of the SSD trial is to pick a desirable treatment arm (e.g., in terms of the median survival time) to recommend to the subsequent randomized phase IIb (with the concurrent control) or phase III. Though The survival endpoint is often encountered in phase II trials, the existing SSD methods cannot deal with the survival endpoint. Furthermore, the existing SSD won’t control the type I error rate. The proposed designs can “partially” control or provide the empirical type I error/false positive rate by an optimal algorithm (implemented by the optimal() function) for each arm. All the design needed components (sample size, operating characteristics) are supported.

Key Metrics

Version 0.1.1
Published 2022-04-15 414 days ago
Needs compilation? no
License GPL-2
CRAN checks frequentistSSD results

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Maintainer

Maintainer

Chia-Wei Hsu

Chia-Wei.Hsu@stjude.org

Authors

Chia-Wei Hsu

aut / cre

Haitao Pan

aut

Jianrong Wu

aut

Material

Reference manual
Package source

macOS

r-release

arm64

r-oldrel

arm64

r-release

x86_64

r-oldrel

x86_64

Windows

r-devel

x86_64

r-release

x86_64

r-oldrel

x86_64

Old Sources

frequentistSSD archive

Depends

survival