adoptr
Adaptive Optimal Two-Stage Designs
Optimize one or two-arm, two-stage designs for clinical trials with respect to several implemented objective criteria or custom objectives. Optimization under uncertainty and conditional (given stage-one outcome) constraints are supported. See Pilz et al. (2019) doi:10.1002/sim.8291 and Kunzmann et al. (2021) doi:10.18637/jss.v098.i09 for details.
- Version1.1.1
- R versionunknown
- LicenseMIT
- LicenseLICENSE
- Needs compilation?No
- adoptr citation info
- Last release10/02/2024
Documentation
- VignetteGet started with adoptr
- VignetteThe adoptr Package: Adaptive Optimal Designs for Clinical Trials in R
- VignetteComposite Scores
- VignetteConditional Scores and Constraints
- VignetteDefining New Scores
- VignetteDesigns for non-normal Endpoints with approximately normal test statistics
- VignetteWorking with priors
- MaterialREADME
- MaterialNEWS
Team
Maximilian Pilz
Jan Meis
Show author detailsRolesAuthorKevin Kunzmann
Show author detailsRolesAuthor, Copyright holderNico Bruder
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Dependencies
- Imports2 packages
- Suggests12 packages
- Reverse Depends1 package