TreeDimensionTest

Testing for trajectory presence and heterogeneity on multivariate data. Two statistical methods (Tenha & Song 2022) doi:10.1371/journal.pcbi.1009829 are implemented. The tree dimension test quantifies the statistical evidence for trajectory presence. The subset specificity measure summarizes pattern heterogeneity using the minimum subtree cover. There is no user tunable parameters for either method. Examples are included to illustrate how to use the methods on single-cell data for studying gene and pathway expression dynamics and pathway expression specificity.