CRAN/E | SurvMI

SurvMI

Multiple Imputation Method in Survival Analysis

Installation

About

In clinical trials, endpoints are sometimes evaluated with uncertainty. Adjudication is commonly adopted to ensure the study integrity. We propose to use multiple imputation (MI) introduced by Robin (1987) doi:10.1002/9780470316696 to incorporate these uncertainties if reasonable event probabilities were provided. The method has been applied to Cox Proportional Hazard (PH) model, Kaplan-Meier (KM) estimation and Log-rank test in this package. Moreover, weighted estimations discussed in Cook (2004) doi:10.1016/S0197-2456(00)00053-2 were also implemented with weights calculated from event probabilities. In conclusion, this package can handle time-to-event analysis if events presented with uncertainty by different methods.

Key Metrics

Version 0.1.0
R ≥ 3.4.0
Published 2020-07-13 1233 days ago
Needs compilation? no
License GPL-2
CRAN checks SurvMI results

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Maintainer

Maintainer

Yiming Chen

yimingc1208@gmail.com

Authors

Yiming Chen

aut / cre

John Lawrence

ctb

Material

Reference manual
Package source

macOS

r-release

arm64

r-oldrel

arm64

r-release

x86_64

r-oldrel

x86_64

Windows

r-devel

x86_64

r-release

x86_64

r-oldrel

x86_64

Depends

R ≥ 3.4.0

Imports

survival ≥ 3.1.11
zoo
stats
graphics
base