CRAN/E | SMDIC

SMDIC

Identification of Somatic Mutation-Driven Immune Cells

Installation

About

A computing tool is developed to automated identify somatic mutation-driven immune cells. The operation modes including: i) inferring the relative abundance matrix of tumor-infiltrating immune cells and integrating it with a particular gene mutation status, ii) detecting differential immune cells with respect to the gene mutation status and converting the abundance matrix of significant differential immune cell into two binary matrices (one for up-regulated and one for down-regulated), iii) identifying somatic mutation-driven immune cells by comparing the gene mutation status with each immune cell in the binary matrices across all samples, and iv) visualization of immune cell abundance of samples in different mutation status..

Key Metrics

Version 0.1.4
R ≥ 3.5.0
Published 2023-08-29 96 days ago
Needs compilation? no
License GPL-2
License GPL-3
CRAN checks SMDIC results

Downloads

Last 24 hours 1 -88%
Last 7 days 60 +30%
Last 30 days 237 +9%
Last 90 days 677 +10%
Last 365 days 2.281 -2%

Maintainer

Maintainer

Junwei Han

hanjunwei1981@163.com

Authors

Baotong Zheng
Junwei Han

Material

Reference manual
Package source

In Views

Omics

Vignettes

SMDIC

macOS

r-release

arm64

r-oldrel

arm64

r-release

x86_64

r-oldrel

x86_64

Windows

r-devel

x86_64

r-release

x86_64

r-oldrel

x86_64

Old Sources

SMDIC archive

Depends

R ≥ 3.5.0

Imports

GSVA
samr
e1071
parallel
preprocessCore
pheatmap
maftools
grDevices
survival
survminer
MASS
pracma
stats
RColorBrewer
backports

Suggests

knitr
rmarkdown
R.utils