RsqMed

An implementation of calculating the R-squared measure as a total mediation effect size measure and its confidence interval for moderate- or high-dimensional mediator model. It gives an option to filter out non-mediators using variable selection method. The original R package is directly related to the paper "Estimation of mediation effect for high-dimensional omics mediators with application to the Framingham Heart Study" with doi:10.1101/774877. The new version contains a choice of using cross-fitting, which is computationally faster.