CRAN/E | PRSPGx

PRSPGx

Construct PGx PRS

Installation

About

Construct pharmacogenomics (PGx) polygenic risk score (PRS) with PRS-PGx-Unadj (unadjusted), PRS-PGx-CT (clumping and thresholding), PRS-PGx-L, -GL, -SGL (penalized regression), PRS-PGx-Bayes (Bayesian regression). Package is based on ”Pharmacogenomics Polyenic Risk Score for Drug Response Prediction Using PRS-PGx Methods” by Zhai, S., Zhang, H., Mehrotra, D.V., and Shen, J., 2021 (submitted).

Key Metrics

Version 0.3.0
R ≥ 4.0.0
Published 2022-07-20 646 days ago
Needs compilation? yes
License GPL-2
License GPL-3
CRAN checks PRSPGx results

Downloads

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Maintainer

Maintainer

Song Zhai

zsviolet1993@gmail.com

Authors

Song Zhai

aut / cre

Material

Reference manual
Package source

Vignettes

Put the title of your vignette here

macOS

r-release

arm64

r-oldrel

arm64

r-release

x86_64

r-oldrel

x86_64

Windows

r-devel

x86_64

r-release

x86_64

r-oldrel

x86_64

Old Sources

PRSPGx archive

Depends

R ≥ 4.0.0

Imports

gglasso ≥ 1.5.0
SGL ≥ 1.3.0
glmnet ≥ 4.0.2
bigsnpr ≥ 1.5.2
Matrix ≥ 1.2.18
GIGrvg ≥ 0.5.0
MCMCpack ≥1.4.6
bdsmatrix ≥ 1.3.4
bigsparser ≥ 0.4.0
lmtest ≥0.9.37
mvtnorm ≥ 1.1.0
propagate ≥ 1.0.6
bigparallelr ≥ 0.2.3
methods ≥ 3.6.3
bigstatsr ≥ 1.2.3
Rfast ≥1.9.9
matrixcalc ≥ 1.0-3

Suggests

knitr
rmarkdown