MetChem

Chemical Structural Similarity Analysis

CRAN Package

A new pipeline to explore chemical structural similarity across metabolite. It allows to classify metabolites in structurally-related modules and identify common shared functional groups. KODAMA algorithm is used to highlight structural similarity between metabolites. See Cacciatore S, Tenori L, Luchinat C, Bennett PR, MacIntyre DA. (2017) Bioinformatics doi:10.1093/bioinformatics/btw705, Cacciatore S, Luchinat C, Tenori L. (2014) Proc Natl Acad Sci USA doi:10.1073/pnas.1220873111, and Abdel-Shafy EA, Melak T, MacIntyre DA, Zadra G, Zerbini LF, Piazza S, Cacciatore S. (2023) Bioinformatics Advances doi:10.1093/bioadv/vbad053.


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