Installation
About
Identify Cancer Dysfunctional Sub-pathway by integrating gene expression, DNA methylation and copy number variation, and pathway topological information. 1)We firstly calculate the gene risk scores by integrating three kinds of data: DNA methylation, copy number variation, and gene expression. 2)Secondly, we perform a greedy search algorithm to identify the key dysfunctional sub-pathways within the pathways for which the discriminative scores were locally maximal. 3)Finally, the permutation test was used to calculate statistical significance level for these key dysfunctional sub-pathways.
Citation | ICDS citation info |
Key Metrics
Downloads
Yesterday | 20 0% |
Last 7 days | 58 -2% |
Last 30 days | 225 +8% |
Last 90 days | 651 -22% |
Last 365 days | 2.780 +15% |