CRAN/E | ICBioMark

ICBioMark

Data-Driven Design of Targeted Gene Panels for Estimating Immunotherapy Biomarkers

Installation

About

Implementation of the methodology proposed in 'Data-driven design of targeted gene panels for estimating immunotherapy biomarkers', Bradley and Cannings (2021) . This package allows the user to fit generative models of mutation from an annotated mutation dataset, and then further to produce tunable linear estimators of exome-wide biomarkers. It also contains functions to simulate mutation annotated format (MAF) data, as well as to analyse the output and performance of models.

Key Metrics

Version 0.1.4
R ≥ 2.10
Published 2021-11-15 865 days ago
Needs compilation? no
License MIT
License File
CRAN checks ICBioMark results

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Maintainer

Maintainer

Jacob R. Bradley

cobrbradley@gmail.com

Authors

Jacob R. Bradley

aut / cre

Timothy I. Cannings

aut

Material

README
NEWS
Reference manual
Package source

macOS

r-release

arm64

r-oldrel

arm64

r-release

x86_64

r-oldrel

x86_64

Windows

r-devel

x86_64

r-release

x86_64

r-oldrel

x86_64

Old Sources

ICBioMark archive

Depends

R ≥ 2.10

Imports

stats
utils
glmnet
Matrix
dplyr
purrr
latex2exp
matrixStats
ggplot2
gglasso
PRROC

Suggests

testthat ≥ 2.1.0