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DNA methylation is essential for human, and environment can change the DNA methylation and affect body status. Epigenome-Wide Mediation Analysis Study (EMAS) can find potential mediator CpG sites between exposure (x) and outcome (y) in epigenome-wide. For more information on the methods we used, please see the following references: Tingley, D. (2014) doi:10.18637/jss.v059.i05, Turner, S. D. (2018) doi:10.21105/joss.00731, Rosseel, D. (2012) doi:10.18637/jss.v048.i02.
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