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DYNATE

Dynamic Aggregation Testing

Installation

About

A multiple testing procedure aims to find the rare-variant association regions. When variants are rare, the single variant association test approach suffers from low power. To improve testing power, the procedure dynamically and hierarchically aggregates smaller genome regions to larger ones and performs multiple testing for disease associations with a controlled node-level false discovery rate. This method are members of the family of ancillary information assisted recursive testing introduced in Pura, Li, Chan and Xie (2021) and Li, Sung and Xie (2021) .

Key Metrics

Version 0.1
R ≥ 3.5.0
Published 2022-10-14 549 days ago
Needs compilation? no
License GPL-3
CRAN checks DYNATE results

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Maintainer

Maintainer

Xuechan Li

xuechanli0530@gmail.com

Authors

Xuechan Li

aut / cre

Jichun Xie

ctb

Material

README
Reference manual
Package source

Vignettes

DYNATE

macOS

r-release

arm64

r-oldrel

arm64

r-release

x86_64

r-oldrel

x86_64

Windows

r-develnot available

x86_64

r-releasenot available

x86_64

r-oldrelnot available

x86_64

Depends

R ≥ 3.5.0

Imports

data.table
tidyverse
Matrix
reshape2
stats
methods
tibble
dplyr

Suggests

knitr
rmarkdown