CRAN/E | DTSEA

DTSEA

Drug Target Set Enrichment Analysis

Installation

About

It is a novel tool used to identify the candidate drugs against a particular disease based on the drug target set enrichment analysis. It assumes the most effective drugs are those with a closer affinity in the protein-protein interaction network to the specified disease. (See Gómez-Carballa et al. (2022) doi:10.1016/j.envres.2022.112890 and Feng et al. (2022) doi:10.7150/ijms.67815 for disease expression profiles; see Wishart et al. (2018) doi:10.1093/nar/gkx1037 and Gaulton et al. (2017) doi:10.1093/nar/gkw1074 for drug target information; see Kanehisa et al. (2021) doi:10.1093/nar/gkaa970 for the details of KEGG database.)

Key Metrics

Version 0.0.3
R ≥ 4.0.0
Published 2022-11-06 526 days ago
Needs compilation? no
License GPL-2
License GPL-3
CRAN checks DTSEA results

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Maintainer

Maintainer

Junwei Han

hanjunwei1981@163.com

Authors

Junwei Han

aut / cre / cph

Yinchun Su

aut

Material

README
NEWS
Reference manual
Package source

Vignettes

DTSEA User Guide

macOS

r-release

arm64

r-oldrel

arm64

r-release

x86_64

r-oldrel

x86_64

Windows

r-devel

x86_64

r-release

x86_64

r-oldrel

x86_64

Old Sources

DTSEA archive

Depends

R ≥ 4.0.0

Imports

dplyr
fgsea
igraph
magrittr
tibble
tidyr
BiocParallel
stringr

Suggests

knitr
rmarkdown