CRAN/E | epoc

epoc

Endogenous Perturbation Analysis of Cancer

Installation

About

Estimates sparse matrices A or G using fast lasso regression from mRNA transcript levels Y and CNA profiles U. Two models are provided, EPoC A where AY + U + R = 0 and EPoC G where Y = GU + E, the matrices R and E are so far treated as noise. For details see the manual page of 'lassoshooting' and the article Rebecka Jörnsten, Tobias Abenius, Teresia Kling, Linnéa Schmidt, Erik Johansson, Torbjörn E M Nordling, Bodil Nordlander, Chris Sander, Peter Gennemark, Keiko Funa, Björn Nilsson, Linda Lindahl, Sven Nelander (2011) doi:10.1038/msb.2011.17.

Key Metrics

Version 0.2.6-1.1
R ≥ 2.12.0
Published 2019-08-26 1712 days ago
Needs compilation? no
License LGPL-3
CRAN checks epoc results

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Maintainer

Maintainer

Tobias Abenius

Tobias.Abenius@Chalmers.se

Authors

Rebecka Jornsten
Tobias Abenius
Sven Nelander

Material

ChangeLog
Reference manual
Package source

macOS

r-release

arm64

r-oldrel

arm64

r-release

x86_64

r-oldrel

x86_64

Windows

r-devel

x86_64

r-release

x86_64

r-oldrel

x86_64

Old Sources

epoc archive

Depends

R ≥ 2.12.0
lassoshooting ≥ 0.1.4
Matrix
methods

Imports

irr
elasticnet
survival

Suggests

graph