CRAN/E | PKNCA

PKNCA

Perform Pharmacokinetic Non-Compartmental Analysis

Installation

About

Compute standard Non-Compartmental Analysis (NCA) parameters for typical pharmacokinetic analyses and summarize them.

Citation PKNCA citation info
billdenney.github.io/pknca/
github.com/billdenney/pknca
billdenney.github.io/pknca/
Bug report File report

Key Metrics

Version 0.10.2
Published 2023-04-29 364 days ago
Needs compilation? no
License AGPL-3
CRAN checks PKNCA results
Language en-US

Downloads

Yesterday 33 0%
Last 7 days 183 -28%
Last 30 days 931 -11%
Last 90 days 3.071 -24%
Last 365 days 14.881 +11%

Maintainer

Maintainer

Bill Denney

wdenney@humanpredictions.com

Authors

Bill Denney

aut / cre

Clare Buckeridge

aut

Sridhar Duvvuri

ctb

Material

README
NEWS
Reference manual
Package source

In Views

MixedModels
Pharmacokinetics

Vignettes

Introduction to PKNCA and Usage Instructions
Computing NCA Parameters for Theophylline
Selection of Calculation Intervals
Sparse NCA Calculations
AUC Calculation with PKNCA
Half-Life Calculation
Post-Processing
Unit Assignment and Conversion with PKNCA
Data Imputation
Superposition of Pharmacokinetic Data
Methods Used for Dose-Aware Concentration Interpolation/Extrapolation
Noncompartmental evaluation of time to steady-state
PKNCA Training Sessions
Options for Controlling PKNCA
PKNCA Validation
Writing PKNCA Parameter Functions

macOS

r-release

arm64

r-oldrel

arm64

r-release

x86_64

r-oldrel

x86_64

Windows

r-devel

x86_64

r-release

x86_64

r-oldrel

x86_64

Old Sources

PKNCA archive

Imports

checkmate
dplyr ≥ 0.5.0
digest
nlme
purrr
rlang
stats
tidyr
tibble
utils

Suggests

covr
cowplot
ggplot2
knitr
labeling
pander
pmxTools
rmarkdown
spelling
testthat ≥ 3.0.0
units
withr

Reverse Depends

respirometry

Reverse Imports

pmxTools
ubiquity

Reverse Suggests

babelmixr2