CRAN/E | CIEE

CIEE

Estimating and Testing Direct Effects in Directed Acyclic Graphs using Estimating Equations

Installation

About

In many studies across different disciplines, detailed measures of the variables of interest are available. If assumptions can be made regarding the direction of effects between the assessed variables, this has to be considered in the analysis. The functions in this package implement the novel approach CIEE (causal inference using estimating equations; Konigorski et al., 2018, doi:10.1002/gepi.22107) for estimating and testing the direct effect of an exposure variable on a primary outcome, while adjusting for indirect effects of the exposure on the primary outcome through a secondary intermediate outcome and potential factors influencing the secondary outcome. The underlying directed acyclic graph (DAG) of this considered model is described in the vignette. CIEE can be applied to studies in many different fields, and it is implemented here for the analysis of a continuous primary outcome and a time-to-event primary outcome subject to censoring. CIEE uses estimating equations to obtain estimates of the direct effect and robust sandwich standard error estimates. Then, a large-sample Wald-type test statistic is computed for testing the absence of the direct effect. Additionally, standard multiple regression, regression of residuals, and the structural equation modeling approach are implemented for comparison.

Citation CIEE citation info

Key Metrics

Version 0.1.1
Published 2018-03-19 2219 days ago
Needs compilation? no
License GPL-2
CRAN checks CIEE results

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Maintainer

Maintainer

Stefan Konigorski

stefan.konigorski@gmail.com

Authors

Stefan Konigorski

aut / cre

Yildiz E. Yilmaz

ctb

Material

Reference manual
Package source

In Views

CausalInference

Vignettes

Estimating and Testing Direct Effects in Directed Acyclic Graphs using Estimating Equations

macOS

r-release

arm64

r-oldrel

arm64

r-release

x86_64

r-oldrel

x86_64

Windows

r-devel

x86_64

r-release

x86_64

r-oldrel

x86_64

Old Sources

CIEE archive

Imports

stats
survival

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