CRAN/E | ActiveDriverWGS

ActiveDriverWGS

A Driver Discovery Tool for Cancer Whole Genomes

Installation

About

A method for finding an enrichment of cancer simple somatic mutations (SNVs and Indels) in functional elements across the human genome. 'ActiveDriverWGS' detects coding and noncoding driver elements using whole genome sequencing data. The method is part of the following publication: Candidate Cancer Driver Mutations in Distal Regulatory Elements and Long-Range Chromatin Interaction Networks. Molecular Cell (2020) doi:10.1016/j.molcel.2019.12.027.

Key Metrics

Version 1.2.0
R ≥ 3.5
Published 2022-09-03 601 days ago
Needs compilation? no
License GPL-3
CRAN checks ActiveDriverWGS results

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Maintainer

Maintainer

Juri Reimand

juri.reimand@utoronto.ca

Authors

Juri Reimand

aut / cre

Helen Zhu

aut

Kevin Cheng

ctb

Material

README
NEWS
Reference manual
Package source

Vignettes

ActiveDriverWGS

macOS

r-release

arm64

r-oldrel

arm64

r-release

x86_64

r-oldrel

x86_64

Windows

r-devel

x86_64

r-release

x86_64

r-oldrel

x86_64

Old Sources

ActiveDriverWGS archive

Depends

R ≥ 3.5

Imports

BSgenome
BSgenome.Hsapiens.UCSC.hg19
BSgenome.Hsapiens.UCSC.hg38
BSgenome.Mmusculus.UCSC.mm9
BSgenome.Mmusculus.UCSC.mm10
Biostrings
GenomeInfoDb
GenomicRanges
IRanges
S4Vectors

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