ThreeArmedTrials

Design and analyze three-arm non-inferiority or superiority trials which follow a gold-standard design, i.e. trials with an experimental treatment, an active, and a placebo control. Method for the following distributions are implemented: Poisson (Mielke and Munk (2009) ), negative binomial (Muetze et al. (2016) doi:10.1002/sim.6738), normal (Pigeot et al. (2003) doi:10.1002/sim.1450; Hasler et al. (2009) doi:10.1002/sim.3052), binary (Friede and Kieser (2007) doi:10.1002/sim.2543), nonparametric (Muetze et al. (2017) doi:10.1002/sim.7176), exponential (Mielke and Munk (2009) ).